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Proteomic and bioinformatic analysis of epithelial tight junction reveals an unexpected cluster of synaptic molecules

in Biology Direct 2006, 1:37



Hits confirmed by other studies

Hit
Title of Paper
Link to Abstract
Tuberin
Evidence for a molecular link between the Tuberous Sclerosis complex and the Crumbs complex
PECAM-1 (CD31)
PECAM-1 (CD 31) mediates transendothelial leukocyte migration in experimental colitis
14-3-3
Interaction of Ubinuclein-1, a nuclear and adhesion junction protein, with the 14-3-3 epsilon protein in epithelial cells: implication of the PKA pathway.

Conti et. al.

alpha-actinin
α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junction

Tang et. al.

FSGS3/CD2AP
FSGS3/CD2AP is a barbed-end capping protein that stabilizes actin and strengthens adherens junctions

Tang et. al.

Synaptopodin
Synaptopodin couples epithelial contractility to α-actinin-4-dependent junction maturation

Kannan et. al.

EPLIN
Epithelial protein lost in neoplasm (EPLIN) interacts with α-catenin and actin filaments in endothelial cells and stabilizes vascular capillary network in vitro.

Chervin-Petinot et. al.

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